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Osteonecrosis of the Jaw. Zometa,Aredia,Fosamax linked to Jaw
By: fc, Sun Aug 20th, 2006
a href="http://www.mpowelllaw.com">Osteonecrosis of the
Jaw. Zometa,Aredia,and Fosamax are common drugs that have
been linked to the loss of jaw bone
These drugs are a type of drug known as bisphosphonates.
Recently a link has been found between bisphosphonates and a
serious bone disease called osteonecrosis of the jaw (ONJ). This
important discovery clearly shows that Fosamax and Zometa side
effects may include osteonecrosis of the jaw, also known as
The discovery, published in the Journal of Oral and
Maxillofacial Surgeons, prompted both the US, Food and Drug
Administration ( FDA ) and Novartis, the manufacturer of
bisphosphonates used in cancer chemotherapy, to issue a warning
to health care professionals on September 24, 2004. The warning
letter contained information about bisphosphonates and the risks
of osteonecrosis in the jaw. Bisphosphonates are commonly used
in tablet form such as Fosamax ( Alendronate Sodium ) to prevent
and treat osteoporosis in post-menopausal women. Stronger forms
of bisphosphonates are commonly used in the management of
advanced cancers that have metastasized to the bone, where the
disease often causes bone pain and possibly even fractures.
Several cancers can involve or metastasize to the bone,
including lung cancer, breast cancer, prostate cancer, multiple
myeloma, and others. When bisphosphonates are given in cancer
chemotherapy, the drugs are given intravenously, and usually for
longer periods of time.
Osteonecrosis of the Jaw Osteonecrosis of the jaw ( ONJ ) is a
condition in which the bone tissue in the jaw fails to heal
after minor trauma such as a tooth extraction, causing the bone
to be exposed. The exposure can eventually lead to infection and
fracture and may require long-term antibiotic therapy or surgery
to remove the dying bone tissue. Experts say that prevention and
early treatment of individuals using bisphosphonates such as
Fosamax is extremely important in preserving the jaw bone.
Individuals using Fosomax or other bisphosphonates should
attempt to avoid tooth extractions and other major dental work
while on the drugs.
Although most cases of osteonecrosis of the jaw related to
Fosamax side effects have occured after dental work several
cases have been reported to occur without any prior dental work.
Patients taking Fosamax may be at risk of developing
osteonecrosis. Patients injured by Fosamax side effects may be
entitled to compensation. For more information about the legal
rights of patients contact the offices of
Powell Law Firm, L.C. is the nation's leading law firm for
litigation regarding Bisphosphonate Complications.
for your free, confidential case evaluation at toll-free
888-238-1998 Please state your name and phone number And we will
get back with you promptly or email us at firstname.lastname@example.org
Accepting Inquiries from the U.S. and Internationally
Every case is different. No specific results are implied.
269 South Beverly Drive, Suite 1156, Beverly Hills, CA 90212
More Osteonecrois of the jaw links:
Osteonecrosis of the Jaw
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